Buy DHEA Dhea buy-information-DHEA DHEA products

Dehydroepiandrosterone (DHEA), Prasterone (INN), which is most abundant steroid hormone in humans. Depending on the particular hormone level may be as an estrogen or behave as an androgen.

DHEA is the precursor for both the male sex hormones (androgens), and for female sex hormones (estrogens).

Dhea General

Just as androsterone, it is a metabolic intermediate of testosterone and is thus known as the prohormone.

It is under the doping regulations of the International Olympic Committee banned.

DHEA was discovered in 1934 by Butenandt and Dannenbaum in urine, 1954 for the first time succeeded in the isolation of blood. DHEA has been known about 1980 as a so-called anti-aging hormone.

DHEA biosynthesis

DHEA is produced in men to 100% in the inner layer (zona reticularis) of the adrenal cortex. In women there, only about 70% the other 30% occur in the ovaries.

In the biosynthesis of DHEA formed from cholesterol via the intermediate hydroxy-pregnenolone and pregnenolone. Thereafter, the reaction is carried out to 4-androstenedione, which is in a chemical equilibrium to testosterone. In a next step may then arise from testosterone 17β-estradiol. From 4-androstenedione is also possible the synthesis of estrone, which in turn is in equilibrium with 17β-estradiol.

The body formed by the levels of DHEA are of age and dependent on gender, as well as the concentration of DHEA in the blood is subject to a diurnal rhythm.

The adrenal glands produce in the first few years, only small amounts of DHEA, larger quantities are first detected in the age of six to seven years. The production of DHEA reaches its peak around the age of 25 years and then goes back all the time.

In all ages men have slightly higher DHEA levels than women.

DHEA is metabolized in the liver to sulfate DHEA-S (discovered in 1994).

Studies suggest that the increased concentration of DHEA by training the heart rate variability [4] could and could lead to a corresponding Wirkmuster, as with drugs with anti-depressive effect.

Dhea use and therapeutic efficacy

In Germany, all pro-hormones are considered as medicines and not considered as approved drugs. DHEA is this the only exception. It is used in the evidence-based medicine is currently only as a combination product (together with estradiol, for example in Gynodian ® Depot injection ampoules) for the treatment of characteristic symptoms (hot flashes, sweating, insomnia, depression) in menopausal women or after oophorectomy or radiation castration.

Otherwise, DHEA is of little medical interest, since not a constant blood level can be achieved at physiologically effective testosterone.

In the U.S., DHEA supplements, however classified as dietary supplements since 1994 and are therefore available without a prescription.
DHEA as an anti-aging hormone

Manufacturers of dietary supplements DHEA, among other praises as prolong life. The reason is that DHEA lower the energy consumption of the cells so that the lifetime increases. This and also all other "benefits" of DHEA could be detected so far in Germany is not scientifically sound. The use of DHEA as an anti-aging medicine is therefore categorized according to current knowledge as at least unnecessary.

Prof. Dr. Wolf has this relatively large double-blind, placebo-controlled studies conducted in the elderly and cognitively tested. The results spoke but not for the life-prolonging effects. The studies were published but good because of the perversion of this hormone that a piece has been demonstrated widely (see book: "Effects of Dehydroepiandrostone (DHEA) replacement on CognitivePerformance in Humans: Four Placebo Controlled Double Blind Studies", Göttingen, 1998).

DHEA Promotes release of acetylcholine:

Acetylcholine is a neurotransmitter that transmits nerve impulses from one brain to another cell. Acetylcholine is crucial for short-term memory and protect brain cells against age-associated atrophy. Aging leads to a reduction of the release of acetylcholine in the brain regions where it is needed for learning and memory.

In a study in Brain Research (Sept. 16, 1996), DHEA was administered to rats to measure the effect it produced on acetylcholine release in the hippocampus region of the brain, a critical area for the storage of memory. DHEA significantly increased acetylcholine release above pre-treatment in all doses tested. At the highest dose of DHEA led to a fourfold increase on the release of acetylcholine, compared with the control group.

The scientists concluded that it is the first study to show that a direct effect of DHEA in promoting the release of acetylcholine from brain cells in the hippocampus. This study provides evidence to support the clinical findings that DHEA improves learning and memory, and suggests that it could help prevent Alzheimer's disease and other types of age-related senility.

DHEA increases protection against Alzheimer's senile plaques Cell:

The accumulation of beta-amyloid in brain cells is a primary structural change associated with the development of Alzheimer's disease. Beta-amyloid was defined as "insoluble brick, accumulates in brain cells with age. Beta-amyloid literally clogs the delicate machines and cellular causes brain cells are not functional.

In a study of the Life Sciences (Oct. 4, 1996), the amount of neuro-protector-amyloid precursor protein (APP) and DHEA in the brain cells was investigated. It was found that the amount of DHEA for these cells decreased significantly with age, that DHEA increases nonamyliodogenic membrane-associated APP by 24 percent, and that the secretion of APP in the medium increased by 63 percent. The more nonamyliodogenic APP fragments were, the less beta-amyloid, they will be recognized.

The DHEA Debate:

Stephen Cherniske: This was by conventional HRT with large doses of synthetic hormones. Yes, that was a disaster, since more than 80 million women who are actually at increased risk for breast cancer, stroke, lung and embolism.117 So, since large quantities of synthetic hormones increased disease risk, believe that small amounts of a natural hormone is the same thing, although we have been over this already, and you saw that there was no evidence that DHEA promotes abnormal growth of tissue in the human body. Although studies using human subjects that increase a 50-mg daily dose of DHEA or not systemic blood levels of estradiol.19 Heck, human studies with 200 mg DHEA per day have shown no systemic level of estradiol.118 On the contrary, conversion of DHEA to sex steroids appears on an as needed basis, by an inherent self-regulating activity.

The research shows conclusively that DHEA deficiency contributes significantly to age bone loss in men and women.42, and a recent study of postmenopausal women, shows the considerable ana-bolic benefits you receive from DHEA supplementation. Women in the treatment group experienced improvements in nearly all anabolic (repair) hormones, including DHEA, estrone, estradiol, androstenedione, and testosterone. It is important that none of these steroids increased to a level that would be unsafe. What's more increases in osteocalcin and IGF-1 suggest that 50 mg DHEA could more effective in maintaining bone density as high doses of estrogen and synthetic progestins (conventional HRT).

DHEA supplements and hormone levels:

A small but important study from Italy shows us how DHEA supplements can affect hormone levels in women.
Comment: Given how little real information we have on the effects / side effects of DHEA appropriate additions in postmenopausal women, this great small study from Italy is a welcome addition to our knowledge DHEA Bank. The one-year study involved 32 healthy postmenopausal women ages 50 to 61 The goal was to find out more about how DHEA affects complement overall hormone levels.
Before treatment began, blood tests were performed for measurement of DHEA, DHEAS, estradiol, estrone, testosterone, progesterone, androstenedione, Allopregnanolone, cortisol, beta-endorphin, and sex hormone binding globulin (SHBG). The researchers divided the women into two groups on the basis of low versus high levels of DHEA. This was not surprising, since DHEA levels decline with age that the group was at the lower levels of DHEA on average older than the group with higher levels of DHEA.
Then the group split with higher DHEA levels in two groups: Group A received 10 mg DHEA daily and group B received HRT Estradiol 0.05 mg estradiol patch delivers a daily and 100 mg daily of oral micronized progesterone (natural progesterone in pill form) . The women with low DHEA (group C) received a combination of DHEA and HRT.

Let's take a look at the results of DHEA group:

Group A (DHEA) showed a significant increase in DHEA, DHEAS, androstenedione, and testosterone. It was a modest increase in estrogen, progesterone, Allopregnanolone and beta-endorphin levels and a significant decrease in cortisol levels.
Group B (HRT) showed only a slight (if any) increase in DHEA, DHEAS and testosterone levels, a modest increase in androstenedione and allopregnanlone levels, a significant increase in estrogen, progesterone, beta-endorphin and SHBG levels, and a modest drop in cortisol levels.
Group C (low baseline DHEA, DHEA-HRT treatment) showed a significant increase in DHEA, DHEAS, androstenedione levels and a modest increase in testosterone levels, a significant increase in estrogen, progesterone, beta-endorphin and SHBG levels, a very slight increase in Allopregnanolone, and a modest decline in the Cortisol.

It is important to note that 25 mg DHEA was enough to all hormone levels, especially the androgens and estrogens. Previous research on DHEA was caused by faulty megadoses of DHEA as much as 50 mg daily. It makes no sense to give women (or men) that much DHEA. An overdose is probably the reason why the results of the DHEA research have been inconsistent.
Among the women with low DHEA (group A), DHEA levels rose, and probably spilled over, the hormonal cascade in the other hormones except cortisol. DHEA is a precursor of progesterone not, but maybe it supports the adrenals to make enough for progesterone.

The effects of DHEA:

The effects of DHEA were significantly greater among younger women (group A) than the older women (group C). This may have to do with age or the additional HRT may have the effect of DHEA.
Perhaps the best news of this study is that DHEA had significantly reduced the effect of cortisol. High cortisol is virtually endemic among postmenopausal women in those days, that is a reflection of the stressful life. Chronic high cortisol increases the risk of breast cancer, diabetes, obesity, osteoporosis, glaucoma and neurodegenerative diseases (eg Alzheimer's, Parkinson's, MS).

Of course, the most important effect of DHEA increased androgen (male hormone). This is a very small study, but it suggests that when our DHEA levels low, and cortisol levels are high, it could be supplemented to be advantageous with 5 or 10 mg DHEA daily, especially if you are not using bioidentical hormones. Because DHEA can increase levels of other hormones considerably, it is important to check your hormone levels regularly to keep balance

Younger, healthier SKIN with dhea hormones:

Skin does not seem like the most exciting part of the body, but it is actually a dynamic, complex organ. Understanding its chemistry can help make your skin young and healthy.
So much hormonal activity occurs in the skin that has been called other endocrine glands. Skin has its own immune system and specialized enzymes that no other has part of the body. It is, in short, a very special part of you.

According to research, the skin can not function without hormones. The anti-stress hormone DHEA, and the sleep hormone melatonin is, are both in the human skin. Both will do to other entities with important jobs. DHEA is converted into estrogen and androgen metabolites in the skin. Melatonin is synthesized in the skin and in low concentrations can stimulate cell growth. This type of on-site, organ-specific production of hormones, so-called intracrine biosynthesis, allows different organs for the production of substances that you need, without flooding the entire body with growth factors.

It is important that studies show that both DHEA and melatonin are absorbed by skin when it thematically. A study from CHUL Research Center, Laval University in Quebec, shows that the activity of DHEA applied topically to rodents is greater 85-90 percent than if it orally.

No special support is needed to DHEA and melatonin in the skin. A properly formulated current preparations of melatonin and DHEA will benefit just enough hormone, without the skin enough to escape into the rest of the body. In addition, it is useful to the hormones directly to the skin if skin protection is the goal, since taking hormones may end up anywhere in the body.

Estrogen-skin-improving effects are known. It stimulates collagen production and a moisture factor known as hyaluronic acid. Aging decreases both estrogen and collagen, and enzymes that convert DHEA to estrogen also decline. It is not surprising that women, the synthetic estrogen have thicker, healthier skin, and women who have both estrogen and testosterone that the skin is 48 percent thicker (and healthier) than women who do not either hormone.

DHEA and estrogen, testosterone, the benefits:

Although the exact role of DHEA and melatonin in human skin are still under control, researchers have several mechanisms by which these hormones protect against aging, maintain healthy skin and influence have identified, such as sunlight reacts with skin cells. All three are linked. For example, sunlight and aging suppress immunity and immunity affects health and melatonin and DHEA affect them all.

Skin is such a specialized organ, it has its own immune system. In fact, it was proposed that faulty skin immunity affects the entire immune system of the body. Sunlight can penetrate deep into the skin and immune change directly, or it can lead to changes in the dermis and epidermis, which in turn provoke immune changes. Sunlight also affects hormones ... it decreases melatonin, norepinephrine and acetylcholine and increases cortisol, serotonin, dopamine and GABA.

DHEA has eineHaut-friendly hormones:

DHEA has a beneficial effect beyond its transformation into skin-friendly hormones-DHEA also powerful protective skin effects. A study in the Journal of Surgical Research demonstrates the extraordinary ability of topically applied DHEA to protect the delicate skin blood vessels. Researchers found that if DHEA is used after a serious burn, blood vessels, the burned area are protected, protected and store blood vessels in the skin.

Skin that can die deduct otherwise and stored by DHEA. No one knows for sure how DHEA saves skin in this way, but its anti-inflammatory action has something to do with it. In particular, DHEA affects on a destructive cytokine known as "tumor necrosis factor." At the same time, that DHEA is inhibiting this destructive process, it appears to extend to Healing: DHEA causes edema (swelling) to take on longer, which apparently saves tissue.

DHEA also protects against the daily insults:

DHEA also protects against the daily insults. By maintaining the skin's immunity, DHEA preserves the ability to react to the skin cancer-causing, skin-destroying pollutants in the air, food and water. DHEA also has antioxidant action against peroxyl and superoxide free radicals.

Superoxide defense to do a lot with DHEA may be able to prevent, skin cancer and papillomas (benign tumors). According to a study of the mouse, topically applied DHEA keeps oxidant enzymes in loving bay. Chemicals with carcinogenic potential depend on oxidases for transformation. DHEA-antioxidant action stops. DHEA is another important defense: it keeps chemical carcinogens from binding to DNA. After some very interesting rodent studies, which may, on rock and Research Institute of Temple University in Philadelphia, cancer does not just start, if enough DHEA.

Anti-aging and wrinkle reduction by DHEA with "Life"

DHEA deficiency is one of the main causes of aging of our skin and our cells. The anti-aging means "Life" activates the body's production of the hormone DHEA, and Super is acting against skin aging, wrinkles and other signs of aging.

The result is reflected in reduction of wrinkles, smooth, healthy skin, more vitality and zest for life and look younger

What is DHEA?:

The production is at the age of 25 years at the highest, and then falls steadily to about 5% of the maximum 85 years. For other steroids is not the case. The first precise determination of DHEA production Beach Life, Skiing, City Breaks place to age in 1958 by Max-Fernand Jaylen, a biochemist at the University of Paris. Women produce more DHEA than men.

The precise biological role is currently more or less understood. Because of its precursor role inter alia for sex hormones DHEA was the role of a buffer hormone attributed Which die availability of other steroids influenced. The addition of DHEA in animal and human experiments showed, however, to include effects of aging, cancer and viral infections.

DHEA has long been known to boost immune function. It is of crucial importance for the development of certain mature immune cells and enhanced antibody production. A new study has found that the number of cells secreting interferon-gamma correlated with serum DHEA levels in men, and that the activity of these cells was associated with DHEA in premenopausal women. Thus, DHEA appears to be involved in the modulation of cytokine production. The same is true for one of its metabolites, androstenediol, which has been shown to protect bone marrow function and resistance to infection following exposure to radiation in rodents even more effective than DHEA. Androstenediol was also shown to protect against lethal infection with influenza A virus. Since infection produces an increase in cortisol, which in turn suppresses the immune system, it would be logical to try, this counterregulate immunosuppression with antiglucocorticoid as DHEA.

DHEA and cancer:

Between 1972 and 1997, more than 4,000 publications have been published worldwide to DHEA, to 1991, many studies have demonstrated the positive effect against various types of cancer, atherosclerosis, weight reduction and prolonged life span in animals. From 1994 onwards, the effect was mainly investigated in humans and found similar results so far.

In the U.S. and other countries already DHEA is marketed widely and sometimes referred to as a miracle cure. It is slipping out of the mostly very positive recent publications that DHEA-GABEN die Simmung improve, increase sexual activity and readiness to counteract stress hormones, muscle condition to maintain, strengthen the immune system and reduce cancer and heart disease risk. Even against AIDS, osteoporosis and Alzheimer DHEA should be effective.

DHEA should also be closely linked, brain neurons to protect them from age-related degenerative processes such as Alzheimer's. Not only that such degenerative processes occur most frequently when the DHEA levels are lowest, but the concentration of DHEA in the brain is much higher than in blood. Dr. E. Roberts is a specialist in this field of research. He found that small amounts of DHEA are sufficient to increase the number of nerve cells, increasing the number of their contacts with others and their differentiation in culture has its anzuregen.DHEA results show improved long-term memory in trained mice. DHEA may play a similar role in the human brain.

One of the major publications is from Mohammed Kalimi and William Regelson 1990: "The biological role of DHEA, present in about 24 chapters in scientists from around the world the results of perhaps the most important neurotransmitter DHEA. These are impressive. The preface to the Editor can read:

"DHEA affects diabetes, cancer, tumor formation, skin texture, fatigue, depression, memory and immune responses. This latitude range of clinical application, it is surprising why more books have been on DHEA attachments!"

Early studies from England [Bulbrook, 1962.1971] have shown that DHEA appeared in abnormally low concentrations in women who die Had breast cancer, even up to nine years before the disease was diagnosed. From 5000 women in the study developed breast cancer 27. Had most of the 27 extremely low DHEA levels. If promoting a low level of DHEA breast cancer, the reverse is also permissible?
The Human Growth Hormone is a peptide hormone (protein) that is used in the pituitary gland (hypophysis) is formed of any healthy person and secreted into the blood to reach all the cells of the body thus. The outstanding effect of growth hormone in children is the stimulation of body growth. Moreover, it also stimulated the protein, fat and bone metabolism in order to allow the growth of the organism through the provision of energy and basic materials. Is not there enough growth hormone or missing it altogether, children remain stunted as adults only and reach heights up to 140 cm. On completion of the expansion, it is for the metabolism of man is the most important "constructive" (anabolic) hormones for muscle, connective tissue and bone. Its importance as a "degrading" hormone in fat metabolism is in the favorable influence of lipids in the blood with a reduction of Artherioskleroserisikos. Drugs with the drug growth hormone (hGH) are among the world's ethical drugs, ie the drugs whose effectiveness is proven and for which there is no substitute.

DHEA and tumors Information:

Dr. A. Schwartz of Temple University, USA found that additions of DHEA in cell cultures from the toxicity of carcinogenic Carcinogenic factors) retained. Typically, cell cultures to respond significantly to DNA mutations, changes in cell appearance and a High mortality. In DHEA-GABEN all these effects were reduced significantly. In mice treated with carcinogenic agents were those who received no DHEA breast cancer. In other studies a reduction of the tumor rate was observed up to 80%. [Schwartz, 1981, 1984] The DHEA-known researcher W. Regelsen stated: "Always when DHEA was tested in a model environment for the development of cancer and tumor-inducing, DHEA had preventive effects."

Although DHEA is currently tested in human tumors, we do not yet know whether the effects in humans are similar.

This must be said that mice and rats were used as test objects for a long time before the investigations in humans. The results so far were mostly similar or identical

DHEA helps fight bacteria and virus, including HIV:

Infection with the Human Immunodeficiency Virus (HIV-1) usually not a full-blown AIDS, except after a period of latency. Certain factors have to activate the virus. These factors include antigens, mitogen and cytokines such as tumor necrosis factor alpha (TNF-alpha). Some experts believe that a State is actually the inflammation with the activation of HIV and AIDS progression for unrestricted exchange of blows. If DHEA has potent anti-inflammatory properties, it should be of great interest to prevent HIV-infected patients, could contribute as a high level of DHEA, that the activation of the virus. Although evidence on the basis of only partial, that advice should HIV patients, their DHEA to be as high as possible seems sound.

In fact, it has been shown that DHEA and its synthetic analogs are capable of producing, in part, inhibition of HIV replication. One study found that a specific analog of DHEA, IM28, had a slightly higher activity against HIV replication as DHEA, but on a prize: Though he was more toxic than DHEA. The mechanism of DHEA's Anti-viral action is not completely understood, but its antioxidant properties (perhaps from the estrogenic metabolites) and their effects on metabolic enzymes are probably part of the explanation.

DHEA hormone research:

Another interesting study to investigate the combined use of DHEA, and melatonin was in Korea. He studied the effects of DHEA, melatonin, and the combination of DHEA and melatonin on the release of tumor necrosis factor alpha (TNF-alpha) by mouse macrophages in the presence of anthrax toxin from the anthrax bacteria. The release of inflammatory cytokines such as TNF-alpha is known to play a central role in the development of anthrax. The authors found that DHEA significantly inhibited the anthrax toxin-induced production of TNF-alpha, melatonin was also effective. The combination of DHEA with melatonin, but did not work better than single therapies.

Simultaneously with the discovery of cancer effect of DHEA, the effect of DHEA on genetically obese mice was examined. Although the DHEA-treated mice ate normally, they remained thin. And lived longer than control mice. In another experiment it was found that even middle-aged fat rats lost weight when fed DHEA-supplemented diet. Diabetes, a typical consequence of obesity, has also been a dramatic return

DHEA and female hormones:

DHEA is the main substance of the sex hormones and is converted into androgens (male hormones) and estrogens (female hormone). DHEA also affects the production of the growth factor insulin-like growth factor 1 (IGF-1). IGF-1 may be a "translator", which allows the body know that, for example, DAS (HGH) (see below exploit).

Positive effects of DHEA and HGH:

Many studies have shown DHEA know that the muscle and promotes bone formation and makes the skin appear young. It also improves neurological function and immune function. There are also indications know that DHEA in heart disease, obesity, cancer and autoimmune diseases (lupus, MS, rheumatoid arthritis) helps and protects against osteoporosis. A study from California (SSCYen) reports know that already after 2 weeks DHEA-taking 82% of women and 67% of men felt an increase in general health. Well as better sleep, more tension and balance, improved handling of stress situations was one of the positive effects that DHEA and DHEAS have obviously varied metabolic effects. Here are some of them:

DHEA and HGH is a sex:

As a precursor of the adrenal steroid hormones, can be converted into the target organs and tissues depending on the corresponding enzymes in androgens (male sex hormones) and estrogens (female sex hormones). Ca. 50% of the total androgens in men are formed from these two precursors, in women around. 75%. The liver converts DHEA to DHEAS in the case of oral intake.

Steroid hormones can easily penetrate the lipid solubility because of your cell membranes, are in the cell bound to a receptor and effect as a hormone receptor complex on the DNA (genetic information) in the nucleus, where genes which can be read and implemented. (Enzyme formation).

DHEA and Building Muscle:

Several researchers found that DHEA, the enzyme glucose-6-phosphate dehydrogenase (G6PDH), inhibits an enzyme that breaks down glucose. This will be the so-called pentose phosphate pathway in glucose including ribulose-5-phosphate (converted to nucleotide synthesis) and 3-P-glyceraldehyde, which is re-injected into the glycolysis. Thus, BTS is then formed, which is then converted into acetyl including the precursor of fatty acids and thus the fats. The Pentosephosphatzyklus is particularly relevant in the liver, adipose tissue, adrenal gland, thyroid gland and erythrocytes (red blood cells) play a role, but not in muscles. In most tissues this pathway is, for example, together with the fatty acid synthesis, thus inhibiting the fat synthesis DHEA.

DHEA's antioxidant products:

Furthermore, DHEA stimulates the activity of the antioxidant enzyme catalase in liver, an enzyme that when the material degradation resulting H2O2 (hydrogen peroxide; cytotoxin) breaks down. The entire maturation (stimulation of the formation of mRNA of enzyme genes) of peroxisomes (cell organelles such as: the liver cells), the catalase is contained encouraged. [Mol Pharmacol. 50: 67-74 (1996)]

This antioxidative processes are encouraged. [Biochem. J. 301: 753-8 (1994)]

DHEA enhanced combat the formation of interferon-in activated T-cells (white blood cells, the virus-infected cells).

Thus DHEA protects against viral infections.

DHEA promotes the development of insulin-producing cells and increases insulin sensitivity.

DHEA may reduce the Herzinfarktrisioko considerably. Activation of brain metabolism in the forebrain and other brain parts by

DHEA. It can increase the differentiation of nerve cells.

HGH DHEA and melatonin libido products are:

This could be used in women with substitutive Nebennierenschwäche improve well-being and libido in the U.S. dietary supplement DHEA approved: A German-blind placebo controlled study, 24 women showed an know that 50mg / day DHEA die libido and increased sexual Zufriedenheitsignifikant. (New England Journal of Medicine)

DHEA improves obviously the reepithelialization in patients with burns with autologous skin grafts
were treated. In the placebo-controlled trial with 63 patients led DHEA 10 mg / kg intravenously significantly to improved reepithelialization
One week after surgery.

Studies in America:

Researchers at the National Institute of Mental Health of the United States Rockville, Maryland-treated men and 46 women. They received either 90 mg daily for six weeks, DHEA or a dummy treatment (placebo).
As the American journal "Archives of General Psychiatry in March 2005 reported that the depressive symptoms only in the DHEA group improved significantly Hatten. Side effects occurred in this time of taking DHEA not.
In the U.S., DHEA is a the-counter dietary supplements. In Germany, you can make DHEA a medical prescription import of a pharmacy or obtain by mail order.

DHEA hormone production:

The production of DHEA in the body falls from about. 30mg of 20 years to less than 6 mg per day at the age of 80. According to Dr. W. Regelson, Medical College Virginia, DHEA is one of the best biochemical marker for the chronological age. In some people from taking DHEA during life by 95%, the biggest decline among the major biochemical substances, which is previously known.

In animal studies DHEA extended the life of rodents by 50%. The animals were living not only longer, looked younger. The gray-haired animals could easily control of the Smooth-haired DHEA-treated animals can be distinguished.

DHEA and heart function:

HEAS levels correlate directly with mortality (dying) in humans.

in a 12-year study of 240 men aged 50-79 years, researchers found that DHEAS levels are inversely related to mortality, no matter if heart attack or other causes led to the death. A 1mg/Liter-Anstieg in DHEAS concentration corresponded to 48% reduction of mortality a heart attack. Those with a higher blood level of DHEAS were living longer and an Had a lower risk of heart disease. These results point to the conclusion that use of DHEA as a diagnostic standard to predict disease, mortality and age.

Another recent study tested the effects of minimal doses of DHEA (50mg/Tag) in men and women 40-70 years. After 2 weeks the blood pressure level had doubled the people quickly. They slept better, felt more relaxed, more energy and Hatten responded better to stress. As far as a weight loss was found in the 3 months of nothing.

If the studies in animals and humans are true, a DHEA supplement prevent disease, reduce mortality and prolong the life of the people.

DHEA enhances the immune response of the organism has been proven. Oral and especially subcutaneous doses of DHEA have rodents (mice, rats) saved from deadly infections. [. Endocrinol. 150: S209-S220 (1996)]. For example, agents were tested herpes virus type 2, coxsackie virus B4 (CB4)) Epstein Barr virus, West Nile virus, Sindbis virus, Semliki Forest virus, bacteria (Enterococcus faecalis, Pseudomonas aeruginosa), and parasites: (Cryptosporidium parvum).

DHEA Hgh effect next?:

The side effects of corticosteroids such as reduction of the thymus gland and suppress the immune response occur in DHEA not. DHEA had no direct effect on viruses. The effect is by stimulation of the lymphocytes (white blood cells), Lymphoid organs and immunomodulating cytokinins. DHEA also seems to HIV-infected people a special role to play. Most HIV-infected men have a significantly lower DHEA levels in the blood rather than infected. [J. the American Medical Association 1989,261:1149]. DHEA inhibits the spread of the HIV virus TYP1 in man.

The production is at the age of 25 years at the highest, and then falls steadily to about 5% of the maximum 85 years. For other steroids is not the case. The first precise determination of DHEA production Beach Life, Skiing, City Breaks place to age in 1958 by Max-Fernand Jaylen, a biochemist at the University of Paris. Women produce more DHEA than men.

The precise biological role is currently more or less understood. Because of its precursor role inter alia for sex hormones DHEA was the role of a buffer hormone attributed Which die availability of other steroids influenced. The addition of DHEA in animal and human experiments showed, however, to include effects of aging, cancer and viral infections.

DHEA affects diabetes, cancer, tumor formation, skin texture, fatigue, depression, memory and immune responses:

Between 1972 and 1997, more than 4,000 publications have been published worldwide to DHEA, to 1991, many studies have demonstrated the positive effect against various types of cancer, atherosclerosis, weight reduction and prolonged life span in animals. From 1994 onwards, the effect was mainly investigated in humans and found similar results so far.

DHEA is effective against Alzheimer's disease:

In the U.S. and other countries already DHEA is marketed widely and sometimes referred to as a miracle cure. It is slipping out of the mostly very positive recent publications that DHEA-GABEN die Simmung improve, increase sexual activity and readiness to counteract stress hormones, muscle condition to maintain, strengthen the immune system and reduce cancer and heart disease risk. Even against AIDS, osteoporosis and Alzheimer DHEA should be effective.

DHEA should also be closely linked, brain neurons to protect them from age-related degenerative processes such as Alzheimer's. Not only that such degenerative processes occur most frequently when the DHEA levels are lowest, but the concentration of DHEA in the brain is much higher than in blood. Dr. E. Roberts is a specialist in this field of research. He found that small amounts of DHEA are sufficient to increase the number of nerve cells, increasing the number of their contacts with others and their differentiation in culture has its anzuregen.DHEA results show improved long-term memory in trained mice. DHEA may play a similar role in the human brain.

One of the major publications is from Mohammed Kalimi and William Regelson 1990: "The biological role of DHEA, present in about 24 chapters in scientists from around the world the results of perhaps the most important neurotransmitter DHEA. These are impressive. The preface to the Editor can read:

"DHEA affects diabetes, cancer, tumor formation, skin texture, fatigue, depression, memory and immune responses. This latitude range of clinical application, it is surprising why more books have been on DHEA attachments!"